Unraveling the Intricacies of PICK1: Exploring Its Role in Neuroscience and Beyond

Recombinant Human PRKCA-binding protein (PICK1)

Recombinant Human PRKCA-binding protein (PICK1) is a protein synthesized using genetic engineering techniques. PICK1 is known for its interaction with protein kinase C alpha (PRKCA) and its role in various cellular processes, including neurotransmission, synaptic plasticity, and intracellular signaling. In its recombinant form, PICK1 can be utilized in research to study protein-protein interactions, cellular signaling pathways, and neurological disorders.

 


 Features

Specificity

PICK1 exhibits high specificity in its interaction with protein kinase C alpha (PRKCA) and other binding partners. This specificity enables precise modulation of intracellular signaling pathways and protein-protein interactions.


Modularity

PICK1 contains distinct domains that mediate its interactions with different proteins and cellular structures. This modular architecture allows for versatility in its functions and potential applications.



Molecular Imaging

Recombinant PICK1 can be labeled with fluorescent or radioactive tags to visualize its localization and dynamics within cells. This technique, known as molecular imaging, allows researchers to track PICK1 distribution in real-time and to study its trafficking and localization in response to various stimuli.

Applications 

Neuroscience Research

Recombinant PICK1 can be used to study the molecular mechanisms underlying synaptic function, synaptic transmission, and synaptic plasticity. It can also be employed to investigate the pathophysiology of neurological disorders such as Alzheimer's disease, Parkinson's disease, and addiction.

Molecular Imaging

Recombinant PICK1 can be labeled with fluorescent or radioactive tags to visualize its localization and dynamics within cells. This technique, known as molecular imaging, allows researchers to track PICK1 distribution in real-time and to study its trafficking and localization in response to various stimuli.

Biotechnology

Recombinant PICK1 can be used in biotechnological applications such as protein purification, protein engineering, and biomaterials development. It may also serve as a molecular scaffold for the design of novel protein-based therapeutics or diagnostic agents.

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