AffiREC® Recombinant Human soluble Tumor Necrosis Factor-Related Apoptosis-inducing Ligand Receptor-2
CAT# AFG-BTL-17877
Size: 10 μg
AffiREC® Recombinant Human soluble Tumor Necrosis Factor-Related Apoptosis-inducing Ligand Receptor-2
Research Area
Immunology.
Purity
> 97 % by SDS-PAGE and HPLC analyses..
Source
N/A.
Biological Activity
Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed..Synonyms
sTRAILR2/TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, Human.
Molecular Weight
Approximately 14.8 kDa, a single non-glycosylated polypeptide chain containing 132 amino acids..
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4..
Storage & Stability
-20ºC