AffiREC® Recombinant Human Fibroblast Growth Factor-19

Research Area

Immunology.

Purity

> 95 % by SDS-PAGE and HPLC analyses..

Source

N/A.

Biological Activity

Assay #1: Fully biologically active when compared to standard. The biological activity is measured by its binding ability in a functional ELISA. Immobilized rHuFGF R4 at 5 μg/ml can bind rHuFGF-19 with a linear range of 3-200 ng/ml. Assay #2: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using Mouse Balb/c 3T3 cells is less than 150 ng/ml, corresponding to a specific activity of > 6.7 × 103 IU/mg..

Synonyms

FGF-19, FGF19, Human.

Molecular Weight

Approximately 21.8 kDa, a single non-glycosylated polypeptide chain containing 195 amino acids..

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4..

Storage & Stability

-20ºC