Recombinant Interleukins

Recombinant interleukins are bioengineered cytokines derived from the family of interleukins (ILs), which are key signaling molecules in the immune system. Interleukins mediate communication between immune cells, regulate inflammatory responses, and modulate cellular proliferation, differentiation, and apoptosis. Recombinant forms of interleukins are produced using advanced expression systems, such as bacteria (E. coli), yeast, mammalian cells (e.g., CHO, HEK293), or insect cells, to ensure their proper folding, activity, and biological functionality.

Content of Recombinant Interleukins
  • Molecular Structure:
    • Interleukins are typically expressed as monomeric proteins, but some may naturally dimerize or oligomerize.
    • Recombinant versions include full-length proteins or truncated bioactive domains.
  • Expression Systems:
    • E. coli: Ideal for cost-effective production; produces non-glycosylated forms.
    • Mammalian Cells: Ensures proper glycosylation and folding, critical for certain interleukins.
    • Yeast and Insect Cells: Offer intermediate glycosylation quality and scalability.
  • Purity and Quality:
    • High purity levels (≥95% by SDS-PAGE or HPLC).
    • Endotoxin levels minimized for sensitive applications (<0.01 EU/µg).
Applications of Recombinant Interleukins
  • Cellular and Molecular Studies:
    • Investigating receptor-ligand interactions, signaling pathways, and downstream effects.
    • Analyzing immune cell responses to specific interleukins in vitro and in vivo.
  • Regenerative Medicine:
    • Using interleukins to modulate stem cell differentiation and tissue repair (e.g., IL-4 in wound healing).
    • Supporting chondrogenesis and cartilage repair (e.g., IL-1RA).
  • Diagnostics:
    • As biomarkers for disease progression or treatment efficacy (e.g., IL-6 in inflammation and sepsis).
    • Development of diagnostic kits and assays involving recombinant interleukins.

Recombinant interleukins are indispensable tools for advancing our understanding of the immune system, developing targeted therapies, and improving diagnostic capabilities across a range of diseases.

AffiREC® Recombinant Human IL11 Protein, His Tag
CAT# AFG-KMD-19546
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL21 Protein, His Tag
CAT# AFG-KMD-19557
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL18 Protein, His Tag
CAT# AFG-KMD-19554
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL15 Protein, His Tag
CAT# AFG-KMD-19551
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL13 Protein, Fc Tag
CAT# AFG-KMD-19549
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL6 Protein, His tag
CAT# AFG-KMD-19541
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL24 Protein, His Tag
CAT# AFG-KMD-19560
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL4 Protein, His Tag
CAT# AFG-KMD-19538
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL2 Protein, His Tag
CAT# AFG-KMD-19536
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL9 Protein, His Tag
CAT# AFG-KMD-19544
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL7 Protein, His Tag
CAT# AFG-KMD-19542
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL22 Protein, His Tag
CAT# AFG-KMD-19558
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL16 Protein, His Tag
CAT# AFG-KMD-19552
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL33 Protein, His Tag
CAT# AFG-KMD-19570
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL31 Protein, His Tag
CAT# AFG-KMD-19568
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL12A Protein, His Tag
CAT# AFG-KMD-19547
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL19 Protein, His Tag
CAT# AFG-KMD-19555
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL12B Protein, His Tag
CAT# AFG-KMD-19548
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL6 Protein, Fc Tag
CAT# AFG-KMD-19540
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL25 Protein, His Tag
CAT# AFG-KMD-19561
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL5 Protein, His Tag
CAT# AFG-KMD-19539
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL3 Protein, His Tag
CAT# AFG-KMD-19537
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL10 Protein, His Tag
CAT# AFG-KMD-19545
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL1B Protein, His Tag
CAT# AFG-KMD-19535
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
1,488.50 1488.5 USD
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL30 Protein, His Tag
CAT# AFG-KMD-19567
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL32 Protein, His Tag
CAT# AFG-KMD-19569
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL1A Protein, His Tag
CAT# AFG-KMD-19534
Size: 100 μg
1,488.50 1488.5 USD
AffiREC®​ Recombinant Human IL-17A
CAT# AFG-MNC-162
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-1 alpha
CAT# AFG-MNC-159
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-18
CAT# AFG-MNC-158
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Human IL-1 beta
CAT# AFG-MNC-157
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-34
CAT# AFG-MNC-156
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Human IL-6
CAT# AFG-MNC-155
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Human IL-2
CAT# AFG-MNC-146
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-13
CAT# AFG-MNC-144
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Rat IL-17A
CAT# AFG-MNC-140
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Human IL-19
CAT# AFG-MNC-138
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-4
CAT# AFG-MNC-136
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-10
CAT# AFG-MNC-128
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-6
CAT# AFG-MNC-127
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-2
CAT# AFG-MNC-125
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-1 beta
CAT# AFG-MNC-122
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Human IL-8
CAT# AFG-MNC-121
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Human IL-4
CAT# AFG-MNC-120
Size: 5 µg
204.30 204.3 USD
AffiREC®​ Recombinant Mouse IL-17A
CAT# AFG-MNC-119
Size: 5 µg
204.30 204.3 USD