Antibody Drug Target Recombinant Proteins 

Antibody drug target recombinant proteins are engineered forms of proteins that serve as key targets for therapeutic monoclonal antibodies (mAbs) in various diseases, including cancer, autoimmune disorders, and infectious diseases. These recombinant proteins are used in drug development, structural studies, functional assays, and diagnostics. They play a critical role in validating antibody efficacy, specificity, and mechanism of action.

Content on Antibody Drug Target Recombinant Proteins
  • Structure and Function
    • Membrane-bound Targets: Include receptors like HER2, PD-1, and CD20, which are central to cell signaling and immune regulation.
    • Soluble Proteins: Such as TNF-α and IL-6, involved in inflammation and immune responses.
    • Intracellular Proteins: Processed or secreted components like checkpoint molecules or immune mediators.
    • Serve as critical ligands or receptors in pathways that regulate disease progression.
Applications of Antibody Drug Target Recombinant Proteins
  • Therapeutic Antibody Development
    • Target Identification and Validation: Study the role of target proteins in disease pathogenesis.
    • Antibody Screening: Test binding specificity and affinity of candidate antibodies to recombinant proteins.
    • Mechanism of Action (MoA) Studies: Investigate pathways modulated by antibody-target interactions.
  • Drug Discovery and Screening
    • Develop high-throughput screening assays to identify small molecules or antibodies modulating target activity.
    • Evaluate competitive binding assays to optimize therapeutic antibody candidates.
  • Immunology and Oncology Research
    • Study immune checkpoint molecules like PD-1, PD-L1, and CTLA-4 in cancer immunotherapy.
    • Investigate inflammatory cytokines such as IL-6 and TNF-α for autoimmune diseases.

Antibody drug target recombinant proteins are essential for advancing therapeutic antibody research and development, providing critical insights into target validation, antibody design, and therapeutic efficacy.

AffiREC® Recombinant Human TIGIT Protein, His Tag
CAT# AFG-KMD-19941
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human VSIR Protein, His tag
CAT# AFG-KMD-19940
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human HAVCR2 Protein, His Tag
CAT# AFG-KMD-19939
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human ICOSLG Protein, His Tag
CAT# AFG-KMD-19938
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human ANGPT2 Protein, His Tag
CAT# AFG-KMD-19936
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human GPC3 Protein, His Tag
CAT# AFG-KMD-19935
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human MET Protein, His Tag
CAT# AFG-KMD-19934
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human APP Protein, Fc tag
CAT# AFG-KMD-19933
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human MSLN Protein, His Tag
CAT# AFG-KMD-19932
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human ERBB3 Protein, His Tag
CAT# AFG-KMD-19931
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human CRBN Protein, His tag
CAT# AFG-KMD-19927
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human PCSK9 Protein, His Tag
CAT# AFG-KMD-19926
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human GLP1R Protein, His tag
CAT# AFG-KMD-19925
Size: 100 μg
1,488.50 1488.5 USD
1,488.50 1488.5 USD
AffiREC® Recombinant Human IL1RN Protein, Fc tag
CAT# AFG-KMD-19923
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human C5 Protein, No Tag
CAT# AFG-KMD-19922
Size: 100 μg
1,488.50 1488.5 USD
AffiREC® Recombinant Human VEGFA Protein, MAT Tag
CAT# AFG-KMD-19921
Size: 100 μg
1,488.50 1488.5 USD