P24 Recombinant Proteins
P24 recombinant proteins are engineered proteins derived from the p24 capsid protein of the human immunodeficiency virus (HIV). This protein is a structural component of the viral core and plays a critical role in the assembly, maturation, and stability of the virus. Recombinant versions of p24 are synthesized using advanced expression systems, ensuring high purity and reproducibility for various applications.
Content on P24 Recombinant Proteins
P24 recombinant proteins are typically expressed in Escherichia coli (E. coli) or mammalian cell systems, providing functional and conformational integrity. These proteins are produced under stringent conditions to ensure they retain their immunogenic and biochemical properties. Key characteristics of p24 recombinant proteins include:
- Molecular Weight: Approximately 24 kDa.
- High Purity: Purity levels of >95% (as confirmed by SDS-PAGE and HPLC).
- Activity: Exhibits antigenicity suitable for antibody production and immunological studies.
- Stability: Optimized for long-term storage and experimental reproducibility.
Application of P24 Recombinant Proteins
- Immunoassays: P24 recombinant proteins are widely used as standards or controls in ELISA (enzyme-linked immunosorbent assays) and Western blot assays for detecting HIV infection.
- Vaccine Research: The immunogenic properties of p24 make it a valuable tool in designing vaccine candidates and studying the immune response against HIV.
- Antibody Production: Used for the generation of monoclonal and polyclonal antibodies targeting the p24 antigen.
- Diagnostic Development: Incorporated into diagnostic kits for early detection and monitoring of HIV infection through antigen-based assays.
P24 recombinant proteins are indispensable tools in virology and immunology research, offering high utility in diagnostics, vaccine development, and fundamental studies of HIV biology. Their consistent quality and performance make them critical components in advancing HIV-related research and therapeutic strategies.
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