SCF Recombinant Proteins 

SCF (Stem Cell Factor) recombinant protein is a cytokine essential for hematopoiesis, stem cell proliferation, and differentiation. It interacts with the c-Kit receptor (CD117) to regulate critical processes, including the survival, proliferation, and mobilization of hematopoietic stem cells (HSCs), melanocytes, and germ cells. SCF plays a vital role in embryogenesis, tissue regeneration, and immune responses.

Content of SCF Recombinant Protein

SCF recombinant protein is produced through advanced expression systems such as E. coli, yeast, or mammalian cells to ensure high purity and bioactivity. It is available in both glycosylated and non-glycosylated forms, with options for isoforms (soluble and membrane-bound). SCF is often tagged (e.g., His-tag) for easy purification and detection. The protein is bioactive and retains its ability to bind and activate the c-Kit receptor.

Applications of SCF Recombinant Protein

• Hematopoiesis Research
  SCF is used to study the proliferation and differentiation of hematopoietic stem and progenitor cells in vitro and in vivo.
• Stem Cell Cultivation
  It is a critical supplement for the expansion of stem cells, particularly HSCs, in research and therapeutic applications.
• Cancer Biology
  SCF-c-Kit interactions are studied in the context of tumor microenvironments, particularly in gastrointestinal stromal tumors (GIST) and melanoma.
• Immunology
  SCF is employed to investigate the regulation of mast cells and their role in allergic and inflammatory diseases.
• Tissue Regeneration
  SCF supports research on wound healing and regeneration by promoting cell migration and tissue remodeling.
• Drug Development
  It is used in screening assays to identify modulators of the SCF-c-Kit signaling pathway, with implications for cancer and regenerative medicine.
• Reproductive Biology
  SCF is studied for its role in germ cell development and fertility research.

SCF recombinant protein is indispensable in regenerative medicine, oncology, and immunology, offering a versatile platform for both fundamental and applied biomedical research.