U22 Recombinant Proteins
U22 recombinant protein originates from the study of viral or cellular gene families encoding U-box domain-containing proteins. These proteins are often involved in processes such as ubiquitination, a post-translational modification critical for protein degradation, signaling, and homeostasis. U22 is associated with regulatory pathways in cellular or viral contexts, particularly in immune evasion, signal transduction, or stress response.
Content of U22 Recombinant Protein
U22 recombinant proteins are synthesized using advanced expression systems to ensure proper folding and functionality. These proteins may include affinity tags (e.g., His-tag, GST-tag) for purification and downstream analysis. U22 proteins typically harbor conserved motifs, such as U-box domains, which are central to their role in interacting with other proteins and modulating enzymatic activity, particularly E3 ubiquitin ligase functions.
Applications of U22 Recombinant Protein
- Ubiquitin Pathway Research
U22 proteins are studied for their involvement in ubiquitination, helping elucidate their role in protein turnover and regulation.
- Virology
In the context of viral proteins, U22 may aid in understanding viral strategies for immune evasion and host manipulation.
- Protein-Protein Interaction Studies
Recombinant U22 is used to study its interactions with other cellular or viral proteins, providing insight into its biological roles.
- Drug Screening
U22 recombinant proteins serve as targets for screening small molecules that modulate ubiquitination pathways, with implications in cancer and immune disorders.
- Structural Analysis
Recombinant U22 facilitates crystallography and NMR studies to reveal its three-dimensional structure and interaction interfaces.
- Signal Transduction
U22's regulatory roles in signaling pathways make it a focus for research in stress response and cell cycle regulation.
U22 recombinant proteins are valuable tools for advancing the understanding of ubiquitination and its impact on cellular and viral processes, with applications in therapeutic and diagnostic development.
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